Erik’s current work is focusing on the long-term metabolic changes in the developing brain following mild traumatic brain injury in rats. In his future projects, he plans to encompass the interplay between metabolism and chronic inflammation in the developing brain following mild traumatic brain injury in rats.

Supervisors: Michael Esser, Timothy Shutt

Funding:

Canadian Institute of Health Research (CIHR)

Natural Sciences and Engineering Research Council of Canada (NSERC)

BranchOut Neurological Foundation

Integrated Concussion Research Program (ICRP)

University of Calgary, Cumming School of Medicine (CSM)

Publication

Fraunberger EA, Scola G, Laliberté VL, Duong A, Andreazza AC. Redox Modulations, Antioxidants, and Neuropsychiatric Disorders. Oxid Med Cell Longev, 2016, 4729192. doi:10.1155/2016/4729192

Fraunberger EA, Shutt TE, Esser MJ. Sex-dependent and chronic alterations in behavior and mitochondrial function in a rat model of pediatric mild traumatic brain injury. Brain Inj, 33(4), 534-542. doi:10.1080/02699052.2019.1565898

Sabouny R, Fraunberger E, Geoffrion M, Ng AC, Baird SD, Screaton RA, Shutt TE. The Keap1-Nrf2 Stress Response Pathway Promotes Mitochondrial Hyperfusion Through Degradation of the Mitochondrial Fission Protein Drp1. Antioxid Redox Signal, 27(18), 1447-1459. doi:10.1089/ars.2016.6855

Fraunberger E, Esser MJ. Neuro-Inflammation in Pediatric Traumatic Brain Injury—from Mechanisms to Inflammatory Networks. Brain Sciences. 2019; 9(11):319. https://doi.org/10.3390/brainsci9110319

Contact: erik.fraunberger@ucalgary.ca