Healthy brain aging

Healthy brain aging leads to morphological changes in the cortical, subcortical and vascular structures of the brain. Several changes are also associated with neurological diseases such as Alzheimer’s diseases. Understanding better these changes is important to be able to differentiate pathological versus normal aging at an early stage. To this aim, we use brain magnetic resonance imaging (MRI) and angiography (MRA) from healthy adults and either use extracted features, such as volumes, or the raw images, to quantify and visualize the impact of aging and additional clinical and life behavioral factors on the brain.