Research Publications

2025

M.V.K. Le, N. Pourzadi and J. Gailer. Retention behavior of Hg²⁺, MeHg⁺, thimerosal and phenylmercuric acetate on a C₁₈ RP-HPLC column. J. Chromatogr. A, 1739, 2025, 465546 https://authors.elsevier.com/a/1kAJK4-ggYrBu.

M.I. Attia and J. Gailer. RE-HPLC reveals the L-cysteine mediated degradation of phenylmercuric acetate. J. Inorg. Biochem. 266, 2025, 112851 https://www.sciencedirect.com/science/article/pii/S0162013425000315?via%3Dihub.

N. Pourzadi, L. Chiaverini, M.P. Gieschen, I. Ennen, A. Huetten and J. Gailer. Liquid chromatography-based metallomics and transmission electron microscopy reveal gold nanoparticle surface treatment with vicinal dithiols to abolish protein corona formation. Nanomedicine, 20, 2025, 1127-1138

L. Chiaverini, R. Di Leo, L. Famlonga, M. Pacini, E. Baglini, E. Barresi, M. F. Peana, I. Tolbatov, A. Marrone, D. La Mendola, J. Gailer, T. Marzo. The metal(loid)s' dilemma. What's the next step for a new era of inorganic molecules in medicine? Metallomics, 17, 2025, mfaf013

M.F. Degorge and J. Gailer. Exposure-response relationship of toxic metal(loid)s in mammals: their bioinorganic chemistry is blood is an intrinsic component of the selectivity filters that mediate organ availability. Toxics 13, 2025, 636

M.F. Degorge, S. Mertz and J. Gailer. Degradation of the vaccine additive thimerosal by L-glutathione and L-cysteine at physiological pH. Inorganics 13 2025, 280        

2024

N. Pourzadi and J. Gailer. The emerging application of LC-based metallomics techniques to unravel the bioinorganic chemistry of toxic metal(loid)s (Concept Paper). J. Chromatogr. A, 1736, 2024, 465409.https://authors.elsevier.com/sd/article/S0021-9673(24)00783-0  

N. Pourzadi and J. Gailer. L-cysteine mediated rapid separation of Hg²⁺ and MeHg⁺ by anion-exchange HPLC. J. Chromatogr. A, 1735, 2024, 465309. https://authors.elsevier.com/a/1jjNJ4-ggYqcq

M. Doroudian and J. Gailer. Interaction of carbonic anhydrase I released from red blood cells with human plasma in vitro. Metallomics, 16, 2024, mfae028. https://doi.org/10.1093/mtomcs/mfae028

M. Doroudian, N. Pourzadi, A. Gautam and J. Gailer. Translational toxicology of metal(loid) species: linking their bioinorganic chemistry in the bloodstream to organ damage onset. Biometals, 37, 2024, 739-753. https://link.springer.com/article/10.1007/s10534-023-00537-2

S. Geri, S. Zinnedu, L. Massai, L. Ronga, R. Lobinski, J. Gailer and L. Messori. Mercury binding to proteins disclosed by ESI-MS experiments: the case of three organomercurials. J. Inorg. Biochem. 252, 2024, 112479. https://doi.org/10.1016/j.jinorgbio.2024.112479

J. Gailer. Toward a mechanism-driven integrated framework to link human exposure to multiple toxic metal(loid) species with environmental diseases. Int. J. Mol. Sci. 25, 2024, 3393. https://doi.org/10.3390/ijms25063393

2023

M. Doroudian, M.E. Thibault and J. Gailer. N-acetylcysteine displaces glutathionyl-moieties from Hg²⁺ and MeHg⁺ to form more hydrophobic complexes at near-physiological conditions. Molecules 28, 2023, 6762. https://www.mdpi.com/1420-3049/28/19/6762

A. Gautam and J. Gailer. More effective mobilization of Hg²⁺ from human serum albumin compared to Cd²⁺ by L-cysteine at near-physiological conditions. Toxics 11, 2023, 599. https://www.mdpi.com/2305-6304/11/7/599

A. Gautam, A. Gomez, E. Mendoza Rengifo, G.N. George, I.J. Pickering and J. Gailer. Structural characterization of toxicologically relevant Cd²⁺-L-cysteine complexes. Toxics 11, 2023, 294. https://www.mdpi.com/2305-6304/11/4/294

2022

M. Doroudian and J. Gailer. Integrative metallomics studies of toxic metal(loid) substances at the blood plasma-red blood cell-organ/tumor nexus. Inorganics, 10, 2022, 200. https://www.mdpi.com/2304-6740/10/11/200

Environmental and Biochemical Toxicology: Concepts, Case Studies and Challenges (De Gruyter Textbook), Editors J. Gailer and R.J. Turner, 2022, https://www.amazon.com/Environmental-Biochemical-Toxicology-Concepts-Challenges/dp/3110626241

T.G. Bridle, M. Doroudian, W. White and J. Gailer. Physiologically relevant hCys concentrations mobilize MeHg from rabbit serum albumin to form MeHg-hCys complexes. Metallomics, 14, 2022, mfac010. https://academic.oup.com/metallomics/article-abstract/doi/10.1093/mtomcs/mfac010/6527585

S. Sarpong-Kumankomah, K.B. Knox, M.E. Kelly, G. Hunter, B. Popescu, H. Nichol, K. Kopciuk, H. Ntanda and J. Gailer. Quantification of human plasma metalloproteins in multiple sclerosis, ischemic stroke and healthy controls reveals an association of haptoglobin-hemoglobin complexes with age. PloS One 17, 2022, e0262160. https://doi.org/10.1371/journal.pone.0262160