Publications
Scroll down to view a list of our works.
If I have seen further it is by standing on the shoulders of giants.
Sir Isaac Newton
Borys, B.S., So, T., Colter, J. et al. Optimized serial expansion of human induced pluripotent stem cells using low density inoculation to generate clinically relevant quantities in vertical-wheel bioreactors. Stem Cells Translational Medicine 2020. 1-17 (2020).
Lee, B., Borys, S., Kallos, M.S. et al. Challenges and Solutions for Commercial Scale Manufacturing of Allogeneic Pluripotent Stem Cell Products. Bioengineering (Basel) 7(31). 1-9 (2020).
Borys, B.S., So, T., Roberts, E.L. et al. Large‐scale expansion of feeder‐free mouse embryonic stem cells serially passaged in stirred suspension bioreactors at low inoculation densities directly from cryopreservation. Biotechnology and Bioengineering 117(5). 1316-1328 (2020).
Borys, B.S., Le, A., Roberts, E.L. et al. Using computational fluid dynamics (CFD) modeling to understand murine embryonic stem cell aggregate size and pluripotency distributions in stirred suspension bioreactors. Journal of Biotechnology 304. 16-27 (2019).
Phelps, J., Sanati-Nezhad, A., Ungrin, M., et al. Bioprocessing of Mesenchymal Stem Cells and Their Derivatives: Toward Cell-Free Therapeutics. Stem Cells International 18. 1-23 (2018).
Hsu, C.Y.M., Walsh, T. Borys, B.S. et al. An Integrated Approach toward the Biomanufacturing of Engineered Cell TherapyProducts in a Stirred-Suspension Bioreactor. Molecular Therapy Methods & Clinical Development 9. 376-389 (2018).
Borys, B.S., Roberts, E.L. Le, A. & Michael Kallos. Scale-up of embryonic stem cell aggregate stirred suspension bioreactor culture enabled by computational fluid dynamics modeling. Biochemical Engineering Journal 133. 157-167 (2018).
Agabalyan, N.A., Borys, B.S., Sparks, H.D. et al. Enhanced Expansion and Sustained Inductive Function of Skin-Derived Precursor Cells in Computer-Controlled Stirred Suspension Bioreactors. Stem Cells Translational Medicine 6(2). 434-443 (2016).
Surrao, D.C., Boon, K., Borys, B.S. et al. Large-scale expansion of human skin-derived precursor cells (hSKPs) in stirred suspension bioreactors. Biotechnology and Bioengineering 113(12). 2725-2738 (2016).