Estefania Barreto-Ojeda

My research is focused on computational biophysics. I perform molecular dynamics (MD) simulations using the Martini force field, a coarse-grained approach. My first project as a Ph.D. student addressed lipid-protein interactions in P-glycoprotein (Pgp), the best characterized ABC transporter. Pgp translocates a wide range of substrates, including drugs and lipid-like molecules. I was investigating lipid diffusion (PC/PE) towards the cavity of Pgp: How do the lipids access the cavity of Pgp? Where are located the lipid-binding sites? Is it the same mechanism for lipid diffusion in Pgp regardless of the lipid environment? We addressed these questions very nicely here. 

Currently starting a second project to study membrane curvature induced by prokaryotic and eukaryotic ABC transporters in the open and closed state. 

I am a data visualization fan and machine learning enthusiast. All related to parallel programming and GPUs sounds cool and usually keeps my attention. I am not an android, still a human. 

Teaching Experience

• Machine Learning for Biologists (BIOL 607)
• DNA, Inheritance and Evolution (BIOL 243)

Extracurricular Activities

• VP Finance  BGSA 2019-2020
• Minerva Operation Volunteer 2017-2018