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 Graduate Studies Calendar 2011-2012 Courses of Instruction Course Descriptions C Cellular, Molecular and Microbial Biology CMMB
Cellular, Molecular and Microbial Biology CMMB
CMMB 505 511 519 523 527 530 531 543 545 549 561 563 565 567 637
 

Instruction offered by members of the Department of Biological Sciences in the Faculty of Science.

Department Head - R.M.R. Barclay

†Note: Limited amounts of non-scheduled class time involvement will be required for this course.
 
Cellular, Molecular and Microbial Biology 505       Advanced Developmental Biology
In-depth analyses of the current literature in developmental biology. Emphasis will be on the coordinated regulation of gene expression during development.
Course Hours: H(3S-0)
Prerequisite(s): Cellular, Molecular and Microbial Biology 403 and Biochemistry 401 or 443.
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Cellular, Molecular and Microbial Biology 511       Molecular Biology and Genetics
The concepts of molecular biology as they apply to genetics. Application of current methodology to the understanding of the genetics of prokaryotes, lower and higher eukaryotes (for example: fungi, yeasts, trypanosomes, plants and animals). Genomic organization and function of subcellular organelles such as mitochondria and chloroplasts will also be considered in detail. The mechanism(s) of regulation of gene expression will be discussed in relation to nuclear as well as organelle genomes.
Course Hours: H(3-0)
Prerequisite(s): Cellular, Molecular and Microbial Biology 411.
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Cellular, Molecular and Microbial Biology 519       Advanced Cell Biology
In-depth analysis of current literature in cell biology. Topics include the cytoskeleton, subcellular organization and dynamics, RNA and protein trafficking, and other aspects of eukaryotic cell biology.
Course Hours: H(3-0)
Prerequisite(s): Biology 311 and 331 and one of Biochemistry 401 or 443.
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Cellular, Molecular and Microbial Biology 523       DNA, Genomes and RNA Function
An examination and comparison of the roles of DNA and RNA in the cell. Includes chromatin structure, transcriptional regulation, mechanisms of post-transcriptional regulation at the RNA level, and the diverse roles played by RNA, ranging from information molecules to structural scaffolds to ribozymes.
Course Hours: H(3-0)
Prerequisite(s): Cellular, Molecular and Microbial Biology 411.
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Cellular, Molecular and Microbial Biology 527       Immunology
Comprehensive overview of the immune responses: antibody-antigen interaction, antibody structure, genetics and synthesis, cellular immunology, MHC, phagocytosis, tolerance, autoimmunity, hypersensitivity, tissue rejection, tumour immunology and vaccine production. Responses to viral, bacterial, fungal and parasite infections. Methods for the study of immunology.
Course Hours: H(3-3)
Prerequisite(s): Biology 311 and 331 and Cellular, Molecular and Microbial Biology 343 and one of Biochemistry 401 or 443.
Antirequisite(s): Credit for both Cellular, Molecular and Microbial Biology 527 and 427 will not be allowed.
Notes: Enrolment in this course may be limited. See Program Details in the Faculty of Science section of this Calendar.      
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Cellular, Molecular and Microbial Biology 530       Honours Research Project in Cellular, Molecular and Microbial Biology
Research project under the direction of one or more faculty members in the Department of Biological Sciences. Formal written and oral reports must be presented on completion of this course. Open only to Honours Cellular, Molecular and Microbial Biology students or Honours Biological Sciences students.
Course Hours: F(0-8)
Prerequisite(s): Cellular, Molecular and Microbial Biology 451 and completion of at least 15 full-course equivalents and consent of the Department.
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Cellular, Molecular and Microbial Biology 531       Topics in Cellular Interactions
An exploration of selected topics concerning cell-cell interactions and the interactions of cells with their environment during development, differentiation and disease. Multidisciplinary approaches will be presented, using discussions of seminal research and critical analysis of current literature. Potential topics include cell junctions, cell signaling, cytoskeletal organization, stroma, extracellular matrix remodeling and stem cells.
Course Hours: H(3-0)
Prerequisite(s): Biology 331 and one of Biochemistry 443 or 431 or 401.
Antirequisite(s): Credit for both Cellular, Molecular and Microbial Biology 531 and 507.90 will not be allowed.
Notes: Prior completion of Cellular, Molecular and Microbial Biology 403 is highly recommended and Cellular, Molecular and Microbial Biology 451 or 527 are advantageous.
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Cellular, Molecular and Microbial Biology 543       Environmental Microbiology
Focuses on understanding the interactions of micro-organisms with their environment. Roles of micro-organisms in nutrient cycling, biological control, and biodegradation will be discussed. The use of molecular approaches to identify and characterize microbial communities, and to understand the precise nature of microbial interactions with abiotic and biotic environments will be emphasized. Special topics will include plant-microbe and animal-microbe symbiosis, extreme environments and biotechnological applications of environmental microbiology.
Course Hours: H(3-0)
Prerequisite(s): Cellular, Molecular and Microbial Biology 343 or consent of the Department.
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Cellular, Molecular and Microbial Biology 545       Petroleum Microbiology
Microorganisms can contribute to a more sustainable energy future. Their impact and roles in the fossil fuel industry will be reviewed. Topics will include oilfield souring, biocorrosion, biodegradation, enhanced recovery, upgrading, and bioremediation of contaminated sites.
Course Hours: H(3-0)
Prerequisite(s): Cellular, Molecular and Microbial Biology 343 or consent of the Department.
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Cellular, Molecular and Microbial Biology 549       Microbial Genetics
The structure and function of microbial genes and genomes will be analyzed with state-of-the-art bioinformatics programs. Advances in understanding of mechanisms of genetic exchange in bacteria and bacteriophages, including conjugation, transduction, transformation and lysogeny will be presented together with selected topics in microbial genetics.
Course Hours: H(3-0)
Prerequisite(s): Cellular, Molecular and Microbial Biology 411.
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Cellular, Molecular and Microbial Biology 561       Cancer Biology
Advances in methodology and in theoretical concepts have permitted continuing breakthroughs in our understanding of the organismal, cellular and molecular biology of cancer cells, and in the development of novel strategies for cancer prevention, diagnosis and treatment. These advances will be presented in a comprehensive overview of cancer including issues of demographics and incidence, causation and detection, origins and progression and therapeutic approaches. Emphasis will be placed on the cell and molecular biology of cancer and on the interaction of the cancer cell with the host organism.
Course Hours: H(3-0)
Prerequisite(s): Biology 331 and Cellular, Molecular and Microbial Biology 411 and one of Biochemistry 401 or 443.
Also known as: (Medical Science 561)
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Cellular, Molecular and Microbial Biology 563       Microbial Diversity
An overview of microbial diversity, the evolutionary mechanisms that give rise to it, and the methods used to study it. Topics may include: microbial systematics; characterizing the last universal common ancestor of life; estimating global microbial diversity; “unculturable” microbes and molecular DNA-based methods used to study them in nature; modern cultivation techniques; comparative genomics of microbial species; environmental metagenomics; microbial biogeography and speciation and gene flow in microbial communities.
Course Hours: H(3-0)
Prerequisite(s): Cellular, Molecular and Microbial Biology 343 or consent of the Department.
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Cellular, Molecular and Microbial Biology 565       Advanced Topics In Pathogenic Microbiology
The course will provide a fuller understanding of bacterial diseases using a systems approach and illustrating key paradigms via the consideration of specific pathogens. Topics include: strategies for bacteria surviving host immune responses, bacterial invasion strategies, opportunistic infections, disease Pathogenesis, and antibiotic resistance, challenges of dealing with emerging infections. Lectures, small group interactive sessions, specified readings.
Course Hours: H(3-0)
Prerequisite(s): Cellular, Molecular and Microbial Biology 343 and 431.
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Cellular, Molecular and Microbial Biology 567       Advanced Topics In Immunology
New and emerging themes in immunology, with an emphasis on disease processes such as inflammation in the gut, kidney and lung. Topics include: innate immunity, the inflammasome, sterile inflammation, process and mechanism of immune cell recruitment in different tissues, T cell biology, B cell biology, regulatory immune cells, mucosal immunity, airways responses to virus, mechanisms of food allergies, inflammatory bowel disease. Lectures, small group interactive sessions, specified readings.
Course Hours: H(3-0)
Prerequisite(s): Cellular, Molecular and Microbial Biology 527.
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Graduate Courses

Enrolment in any graduate course requires consent of the Department.

Only where appropriate to a student's program may graduate credit be received for courses numbered 500-599.

600-level courses are available with permission to undergraduate students in the final year of their programs.

 
Cellular, Molecular and Microbial Biology 637       Advanced Topics in Molecular Microbiology
Techniques and discussion of recent literature in molecular microbiology. Topics covered will vary from year to year, but could include bioinformatics, genomics, mutagenesis, advanced microscopy techniques, proteomics, vectors and cloning techniques, gene expression, and over-expression of proteins, as they relate to the study of prokaryotic systems. Course content will be tailored to the interests of the graduate students enrolled in the class in a given year.
Course Hours: H(3-3)
MAY BE REPEATED FOR CREDIT
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