Impact of Biological Sex, Menstrual Cycle, and Fitness Status in the Control of Brain Blood Flow
Summary
This study is exploring how biological sex, fitness level, and the menstrual cycle impacts the control of blood flow in the brain. Individuals will perform a maximal exercise test at the start of testing. They will also perform follow-up visits that will take roughly 90 minutes each. Individuals will perform various tasks that will alter the control of brain blood flow. Several universities across the world have used these tasks in a safe manner. These tasks include repeated squatting, breathing challenges, and visual tasks. Three different technologies that measure brain blood flow will be used during these tasks. These technologies are safe and have been used in many previous research studies.
Currently, there is an underrepresentation of females in research studies. This study is seeking to reduce this gap and help increase the number of future studies including females.
Eligibility
Eligible gender: Male, Female, Transgender, Other
Eligible ages: 18 to 40
Accepts healthy participants: Yes
Inclusion criteria:
Participants will be included if they:
1) are between the ages of 18.00-64.99 years (n=120, 60 females and 60 males);
2) have no history of cerebrovascular, cardiorespiratory, musculoskeletal, or neurological conditions;
3) are able to perform all exercise and orthostatic protocols;
4) provide informed consent.
Exclusion criteria:
Participants will be excluded if they :
1) are obese (body mass index >35 kg/m^2);
2) have a history of smoking;
3) are hypertensive (systolic >145 mmHg and diastolic >95 mmHg)
4) are pregnant or attempting to become pregnant,
5) have a previous history of syncope.
Participate
Fill out the following form if you want to participate in this research
Collection of personal information
Your personal information is collected under
the authority of section 33(c) of the Freedom of Information and Protection of Privacy Act. If
you have any questions about the collection or use of this information, please visit our
Access to Information page.
Additional information
Contact information
Cerebrovascular Concussion Lab Researchers
Principal investigator:
Jonathan Smirl
Clinical trial:
No
REB-ID:
REB20-2112