Marcelo Muscara
Associate Professor
Department of Pharmacology, University of São Paulo
Adjunct Professor
Department of Physiology and Pharmacology, University of Calgary
PhD - Pharmacology
University of São Paulo, Brazil, 1995
MSc - Pharmacology
State University of Campinas (UNICAMP), Brazil, 1991
BSc - Chemistry
University of Buenos Aires, Argentina, 1988
Contact information
Research
Activities
The participation of nitrogen, sulfur and oxygen-derived species in many pathological conditions (such as hypertension, diabetes, neuro-degenerative diseases and several inflammatory processes) is well characterized and is currently being considered as potential focus of pharmacological intervention for effective treatment of these diseases.
Main interests:
- To study the production and control of the gasotransmitters nitric oxide (NO), hydrogen sulfide (H2S) and oxygen-derived reactive species in several diseases (such as endotoxemia, periodontitis, hypertension, psoriasis, atopic dermatitis, pain, asthma, arthritis) making use of experimental animal models and in vitro approaches.
- To study the altered vascular responses associated to the above mentioned diseases.
- To evaluate the effects of new anti-inflammatory therapeutic alternatives based on donation and/or inhibition of the above mentioned gasotransmitters.