Department of Chemistry

Visiting Speaker

Professor James Green, Dept. of Chemistry and Biochemistry, University of Windsor.

Will present a seminar titled:

“Cobalt Stabilized γ-Carbonyl Cations and Cycloheptynes”

Abstract:

The study of γ-carbonyl cations is important as a fundamental form of umpolung synthesis and a challenge in the generation of systems simultaneously retaining a high degree of electrophilicity and a sufficient stability for ready access. Cycloheptynes are of fundamental interest as theoretically interesting transient intermediates, but are infrequently used synthetically in part because of their lack of stability. We will describe our efforts at generating γ- carbonyl cations stabilized as their propargyldicobalt complexes 1, and their reactions, and a number of methods for the preparation of cycloheptynedicobalt complexes 2, as well as some of their reactivity. Ultimately, the use of each of these systems in natural product synthesis (i.e., 3) will be described. In the case of cycloheptyne Co₂(CO)₆ complexes, their use in the preparation of dehydrotropylium ion complexes (i.e., 4) will also be discussed.

Tuesday, December 13, 2011 @ 11:00 a.m. in SB 324

Department Contact: Dr. Thomas G.  Back

tgback@ucalgary.ca