Publications

Johnson L, Mulcahy H, Kanevets U, Shi Y, Lewenza S.   Surface-localized spermidine protects the Pseudomonas aeruginosa outer membrane from antibiotic treatment and oxidative stress. J Bacteriol. 2012 Feb;194(4):813-26.

Mulcahy H, Sibley CD, Surette MG, Lewenza S.  Drosophila melanogaster as an animal model for the study of pseudomonas aeruginosa biofilm infections in vivo. PLoS Pathog. 2011 Oct;7(10):e1002299

Mulcahy H, Lewenza S. Magnesium limitation is an environmental trigger of the Pseudomonas aeruginosa biofilm lifestyle. PLoS One. 2011;6(8):e23307

Lewenza S, Falsafi R, Bains M, Rohs P, Stupak J, Sprott GD, Hancock RE.  The olsA gene mediates the synthesis of an ornithine lipid in Pseudomonas aeruginosa during growth under phosphate-limiting conditions, but is not involved in antimicrobial peptide susceptibility.    FEMS Microbiol Lett. 320(2):95-102, 2011

Lewenza S, Charron-Mazenod L, Cho JJ, Mechor B.  Identification of bacterial contaminants in sinus irrigation bottles from chronic rhinosinusitis patients . J Otolaryngol Head Neck Surg. 39(4):458-63, 2010

Mulcahy H, Charron-Mazenod L, Lewenza S. Pseudomonas aeruginosa produces an extracellular deoxyribonuclease that is required for utilization of DNA as a nutrient source. Environ Microbiol 12(6):1621-9, 2010

Mulcahy H, Charron-Mazenod L, Lewenza S. Extracellular DNA chelates cations and induces antibiotic resistance in Pseudomonas aeruginosa biofilms. PLoS Pathog 4(11): e1000213, 2008 

Lewenza S, Mhlanga MM, Pugsley AP. Novel inner membrane retention signals in Pseudomonas aeruginosa lipoproteins. J Bacteriol 190(18):6119-25, 2008

Vidal-Ingigliardi D, Lewenza S,, Buddelmeijer N. Identification of essential residues in apolipoprotein N-acyl transferase (LNT), a member of the CN-hydrolase family. J Bacteriol 189(12):4456-64, 2007

Francetic O, Buddelmeijer N, Lewenza S, Kumamoto CA, Pugsley AP. SRP-dependent Inner Membrane Targeting of the PulG Pseudopilin Component of a Type II Secretion System. J Bacteriol 189(5):1783-93, 2007

Overhage J, Lewenza S, Marr AK, Hancock RE. Identification of genes involved in swarming motility using a Pseudomonas aeruginosa PAO1 mini-Tn5-lux mutant library. J. Bacteriol. 189(5): 2164-9 . 2006

McPhee JB, Bains M, Winsor G, Lewenza S, Kwasnicka A, Brazas MD, Brinkman FS, Hancock RE. Contribution of the PhoP-PhoQ and PmrA-PmrB two-component regulatory systems to Mg2+-induced gene regulation in Pseudomonas aeruginosa. J Bacteriol. 188(11):3995-4006. 2006

Lewenza S,Vidal-Ingigliardi D and AP Pugsley.  2006. Direct visualization of red fluorescent lipoproteins indicates conservation of the membrane sorting rules in the Enterobacteriaceae. Journal of Bacteriology 188:3516-3524* Cover article

Lewenza S, Falsafi RK, Winsor G, Gooderham J, McPhee JB, Brinkman  FSL, and REW Hancock 2005. Construction of a mini-Tn5-luxCDABE mutant library in Pseudomonas aeruginosa: a tool for identifying differentially regulated genes. Genome Research 15: 583-589

Lewenza S, Gardy JL, Brinkman FSL, and REW Hancock. 2005. Genome-wide identification of Pseudomonas aeruginosa exported proteins using a consensus computational strategy combined with a laboratory-based PhoA fusion screen. Genome Research 15: 321-329