DR. CAIRINE LOGAN

Assistant Professor, Department of Cell Biology and Anatomy, Genes and Development Research Group

Affiliations: Member - The Alberta Children's Hospital Research Institute for Child and Maternal Health  Associate Member - The Hotchkiss Brain Institute Member: Genes and Development Research Group

Research Interests:

My work focuses on two inter-related areas of developmental neurobiology: 1) pattern formation within the developing central nervous system of the vertebrate embryo and 2) the ontogeny of distinct neuronal systems. More specifically, I am interested in defining the cellular and molecular mechanisms involved in setting up positional information along the rostral-caudal and medial-lateral axis within developing mes/metencephalic derivatives. In addition, I have recently begun to investigate the molecular cues involved in the differentiation of specific neuronal cell types and establishment of neuronal circuitry within the developing cranial sensory system. I use the chick embryo as a model system in which to explore both of these issues and utilize a multidisciplinary approach which combines techniques in molecular biology, electroporation and retroviral-mediated gene transfer, microsurgery, cell and tissue culture, anterograde labelling, as well as immunohistochemistry.  

 Personnel:

View Pub Med for Recent publications & abstracts

Recent Publications:

• Berndt, A. and C. Logan. (2009). Serial analysis of gene expression. In: Encyclopedia of Neuroscience. Binder, M., Hirokawa, N. and Windhorst, U. eds. Springer, USA. (in press).
• Meruvia-Pastor, O., Soh, J., Xiao, M., Schmidt, E., Logan, C.,Boughner, J., Jones, N., Osborn, D., Santiago, J., Gittleman, J., Hallgrimsson, B. and Sensen, C. (2009). Fast interactive integration of cross-sectional image datasets and surface data for morphometric analysis. In: Medicine Meets Virtual Reality 17. NextMed: Design for the Well Being. Westood, J. D., Westwood, S. W., Haluck, R. S., Hoffman, H., Mogel, G. T., Phillips, R., Robb, R. A. and Vosburgh, K.G. eds. IOS Press, USA. pp. 183-186.
• Hallgrimsson, B., Boughner, J. C., Turninsky, A., Parsons, T. E., Logan, C. C., Sensen, C. W. (2009). Geometric morphometrics and the study of development.  In: Advanced Imaging in Biology and Medicine:Technology, Software Environments, Applications. Sensen, C. W. and B. Hallgrimsson, B. eds. Springer Verlag, USA.  pp. 319-339.
• Logan, C. and Francis-West, P. (2008). Gene transfer in avian embryos using replication-competent retroviruses.  In: Methods in Molecular Biology, Vol 461: Molecular Embryology: Methods and Protocols. Sharpe, P. and I. Mason, eds. Humana Press, USA.  pp. 363-376.Langevin, L. M., Mattar, P., Scardigli, R., Roussigné, M., Logan, C., Blader, P. and Schuurmans, C. (2007). Validating in utero electroporation for the rapid analysis of gene regulatory elements in the murine telencephalon. Dev. Dynam. 236: 1273-1286.

Contact Information:

The University of Calgary
Room 2203, Health Sciences Centre
3330 Hospital Drive NW
Calgary, Alberta T2N 4N1
Phone: (403) 220-2489
Lab: (403) 220-2490
Fax: (403) 283-8731
Email: clogan [at] ucalgary [dot] ca