Faculty Listing (A - Z)

• Tara L. Beattie, Ph.D. In vitro reconstitution of human telomerase activity.
• Mark Bieda, Ph.D. High throughput epigenetics and bioinformatics.
• Shirin Bonni, Ph.D. Characterization of Mechanisms and Regulation of TGF-beta Signaling and Biological Responses.
• William J. Brook, Ph.D. Pattern Formation in Drosophila melanogaster development. The control of cell patterning and growth by secreted peptides. Developmental genetic approaches to studying cell-cell interactions and signal transduction.
• Leon W. Browder, Ph.D. Technique of transgenesis to study the roles of Bcl-xL and ING1 in development.
• George Chaconas, Ph.D. Telomere resolution, DNA replication and mechanisms of pathogenesis in Borrelia burgdorferi, the Lyme disease spirochete.
• Sarah J. Childs, Ph.D. Blood vessel development in Zebrafish.
• Jennifer A. Cobb, Ph.D. Genetics and biochemistry of cell cycle checkpoints and RecQ helicases in the maintenance of genomic stability using the model organism Saccharomyces cerevisiae.
• Julie P. Deans, Ph.D. Lymphocyte development, activation and signal transduction.
• Don J. Fujita, Ph.D. Role of src-type oncogenes and cellular effectors in signal transduction, proliferation, cancer, and differentiation.
• Jeffrey (Jeb) Gaudet, Ph.D. Control of organ formation.
• Aaron Goodarzi, Ph.D.Chromatin dynamics during the human response to radiation induced DNA double strand breaks"
• Roy A. Gravel, Ph.D. Genetic basis and consequences of metabolic disease.
• Savraj Grewal, Ph.D. The control of cell growth.
• Frank R. Jirik, M.D., F.R.C.P. (C) 1. Murine models of skeletal development and osteoarthritis 2. Immunoglobulin-induced inflammatory arthritis 3. Breast cancer bone metastasis 4. Role of Pten and SHIP in autoimmunity 5. Carcinogenesis 6. Exploring prion gene function
• Randal N. Johnston, Ph.D. Regulation of expression and function of oncogenes. Control of cancer cell behavior. Cell cycle control, differentiation and apoptosis.
• Sung-Woo Kim, Ph.D. Mouse models of cancer, cell signaling and functional genomics.
• Susan P. Lees-Miller, Ph.D. The role of DNA-PK and ATM in detection and repair of DNA damage.
• Jonathan Lytton, Ph.D. Molecular biology of membrane transport systems involved in systemic and cellular calcium homeostasis.
• Justin A. MacDonald, Ph.D. Analysis of signal transduction pathways that regulate smooth muscle contractility-novel mechanisms of smooth muscle myosin phosphatase and cGMP-phosphodiesterase 5 (PDE5) regulation.
• Paul E. Mains, Ph.D. Genetic and molecular analysis of genes active during embryonic development of C. elegans.
• James D. McGhee, Ph.D. Control of lineage-specific gene expression during early development of the nematode C. elegans.
• Karl T. Riabowol, Ph.D. Regulation of transcription and control of cell growth during cellular aging and oncogenesis.
• David C. Schriemer, Ph.D. Proteomics of complex molecular assemblies; clinical proteomics; technology development for proteomics and drug discovery.
• Carol J. Schuurmans, Ph.D. Neurogenins and the specification of neuronal identity in the cerebral cortex.
• Christoph W. Sensen, Ph.D. Bioinformatics with applications in proteomics and genomics.
• Frans A. van der Hoorn, Ph.D. Regulation of transcription of testis-specific genes and structure-function analyses of their products.
• Michael P. Walsh, Ph.D. Regulation of cellular functions by second messengers, with emphasis on protein phosphorylation and the control of smooth muscle contraction.
• Dallan B. Young, Ph.D. Genetics and biochemistry of signal transduction in yeast and mammalian cells; emphasis on MAP kinase pathways; regulation of cell cycle, growth and differentiation.
• Xi-Long Zheng, Ph.D. To investigate the role(s) of vascular smooth muscle phospholipase D in the development of atherosclerosis, the major cause of cardiovascular diseases.

 

JOINT MEMBERS

• Tarek Bismar, Ph.D
• Christopher B. Brown, M.D., F.R.C.P.(C) Hematopoietic development and function at several levels, both physiological and pathological.
• S. R. Wayne Chen, Ph.D. Structure and function of intracellular Ca2+ channels, with special emphasis on the ryanodine receptor.
• James (Jay) C. Cross, D.V.M. Ph.D. Molecular biology and 'knockout' and transgenic mouse techniques to understand how cell cycle progression and differentiation of cells is orchestrated during embryonic development.
• Douglas J. Demetrick, Ph.D., MD, Regulation of proliferation in cancer cells and molecular pathology/diagnosis of cancer.
• Ina Dobrinski, Dr.med.vet., M.V.Sc., Ph.D.
• Marvin J. Fritzler, Ph.D., M.D., Antigen targets of autoimmune diseases. Special interest in the cell and molecular biology of the Golgi complex, cell cycle antigens and components of the miRNA pathway. Models of autoimmune disease and new diagnostic technologies.
• John Gilleard, Ph.D. Parasitology.
• Dustin Hittel, Ph.D
• Carol Huang, MD, Ph.D. Regulation of beta cell proliferation and function in animal models of diabetes
• Christian J. Jacob, Ph.D. Evolutionary and swarm design.
• Deborah Kurrasch, Ph.D.
•  Greg Moorhead, Ph.D.
• Minh Dang Nguyen, Ph.D. Molecular cell biology of the neuronal cytoskeleton and nucleoskeleton and Neurodegenerative disorders and Aging.
• Kamala D. Patel, Ph.D. Molecular mechanisms of eosinophil adhesion and activation. Structure/functional analysis of vascular adhesion proteins.
• Derrick E. Rancourt, Ph.D. Generation of mouse models of disease via gene targeting, genetic analyisis of mammalian embryonic proteinases, in vitro neural differentiation using murine stem cells.
• Jerome B. Rattner, Ph.D. Identification and characterization of protein components of the kinetochore, centromere and chromosomal surface domain.
• Raylene A. Reimer, Ph.D. Regulation of gene expression by diet, diabetic potential of early diets, and development of in vitro models.
• David C.W. Lau, M.D., Ph.D., F.R.C.P.(C) Paracrine/autocrine, and/or endocrine factors regulating fat cell proliferation and differentiation in health and obesity.
• Greg Moorhead, Ph.D.
• Stephen M. Robbins, Ph.D. Protein-tyrosine kinases and compartmentalized signalling: controlling cell proliferation and differentiation.
• Paul P.M. Schnetkamp, Ph.D. Structure-function studies of membrane proteins involved in cellular calcium and cGMP homeostasis (e.g. Na-Ca exchange and guanylyl cyclase).
• Anthony B. Schryvers, Ph.D. Pathogenesis of bacterial infections and the development of vaccines for their prevention.
• Jane Shearer, Ph.D. Regulation of substrate utilization in metabolic disease states.
• Yan Shi, M.D., Ph.D. Endogenous and microbial adjuvants, their receptors, in antigen presenting cell activation, natural antibodies and nucleic acid in immune regulation.
• Brent W. Winston, M.D. Study of the mechanisms of functional diversity of macrophages, encompasses examining macrophage activation, cell signalling and gene regulation.
• Norman C. W. Wong, M.D. Thyroid hormone regulation of hepatic gene expression. Regulation of apolipoprotein A1 gene expression and gene therapy to enhance apolipoprotein AI levels in patients with heart disease.
• Robin M. Yates, Ph.D. Macrophage function.

 ADJUNCT MEMBERS

• Zenobia Ali, Ph.D. Laboratory coordinator in Masters of Biomedical Technology.
• Mayi Arcellana-Panlilio, Ph.D. Design, production, interrogation, and analysis of microarrays.
• Michael C. Brain, D.M.. Red blood cell hemolysis
• John Chik, Ph.D. Biophysics of molecular forces and their role in protein function and structure.
• Jens Coorssen, Ph.D. Obtaining a comprehensive understanding of Ca2+-triggered fusion steps in exocytosis and endocytosis. Translational proteomics.
• Peter Forsyth, M.D., Neuro-oncology clinical trials; inhibitors of brain cancer invasion and metastasis.
• Lashitew Gedamu, Ph.D. Regulation of metallothionein genes; molecular biology of Leishmania pathogenesis.
• Kostas Iatrou, Ph.D
• Blanka Kuhnel, Ph.D. Biomedical Technology.
• Cairine Logan, Ph.D. Developmental neurobiology
• Denis McMaster, Ph.D. Peptide synthesis and purification.
• Kenneth Ng, Ph.D. Structural biology specializing in the crystallographic analysis of the structures of RNA polymerases of RNA viruses.
• Richard T. Pon, Ph.D. Chemical synthesis of DNA, RNA and oligonucleotide analogs.
• Jesusa (Susie) Rosales, Ph.D. Neutrophil-mediated immune response to injury and infection.
• Navneet Sharma, Ph.D. Identifying substrates for proteases using innovative high throughput technology
• Gary D. Sinclair, Ph.D. Structure, function and evolution of blood clotting factors. Regulation of hemophilia, von Willebrand disease and diabetes.
• Michael Surette, Ph.D. Understanding bacterial signal transduction and physiology with the context of the individual cells and in interacting populations of cells.
• Peter D. Vize, Ph.D. Developmental biology, specializing in the study of kidney development in Xenopus.
• Hans J. Vogel, Ph.D. Characterization of regulatory and metal ion binding proteins by high resolution multinuclear NMR. In vivo NMR studies of plant cell metabolism.
• David M. Waisman, Ph.D. Biochemical and molecular biological studies of plasminogen and its role in fibrinolysis and metastasis.
• James Wasmuth: Ph.D
• Andreas Wissman, Ph.D. Treatment for neurodegenerative diseases and novel analgesics.
• Yang Yang, Ph.D. T cell immunology and autoimmune diabetes.

EMERITUS PROFESSORS

• Fred G. Biddle, Ph.D. Genetic analysis of complex developmental traits in the mouse: sex; meiosis; lateral asymmetry; teratogenic response.
• Robert B. Church, Ph.D.
• Gordon A. Dixon, Ph.D.
• H. Joseph Goren, Ph.D. Insulin receptor signalling pathways: characterization of receptor-associating proteins.
• Gilbert A. Schultz, Ph.D.
• Floyd F. Snyder, Ph.D. Molecular, cellular and mouse model studies of inherited disorders of nucleotide metabolism.
• J. Hans van de Sande, Ph.D. DNA with anomeric centre and polarity reversal as a novel antisense therapeutic agent. Structure-function studies on uracil DNA glycosylase and its role in DNA repair.