Cell Signalling and Structure

• Shirin Bonni, Ph.D. Characterization of Mechanisms and Regulation of TGF-beta Signaling and Biological Responses.
• Michael C. Brain, D.M.. Red blood cell hemolysis.
• Jens Coorssen, Ph.D. Obtaining a comprehensive understanding of Ca2+-triggered fusion steps in exocytosis and endocytosis. Translational proteomics.
• Julie P. Deans, Ph.D. Lymphocyte development, activation and signal transduction.
• Don J. Fujita, Ph.D. Role of src-type oncogenes and cellular effectors in signal transduction, proliferation, cancer, and differentiation.
• H. Joseph Goren, Ph.D. Insulin receptor signalling pathways: characterization of receptor-associating proteins.
• Susan P. Lees-Miller, Ph.D. The role of DNA-PK and ATM in detection and repair of DNA damage.
• Cairine Logan, Ph.D. Developmental neurobiology.
• Jonathan Lytton, Ph.D. Molecular biology of membrane transport systems involved in systemic and cellular calcium homeostasis.
• Justin A. MacDonald, Ph.D. Analysis of signal transduction pathways that regulate smooth muscle contractility-novel mechanisms of smooth muscle myosin phosphatase and cGMP-phosphodiesterase 5 (PDE5) regulation.
• Minh Dang Nguyen, Ph.D. Molecular cell biology of the neuronal cytoskeleton and nucleoskeleton and Neurodegenerative disorders and Aging.
• Kamala D. Patel, Ph.D. Molecular mechanisms of eosinophil adhesion and activation. Structure/functional analysis of vascular adhesion proteins.
• Jerome B. Rattner, Ph.D. Identification and characterization of protein components of the kinetochore, centromere and chromosomal surface domain.
• Karl T. Riabowol, Ph.D. Regulation of transcription and control of cell growth during cellular aging and oncogenesis.
• Stephen M. Robbins, Ph.D. Protein-tyrosine kinases and compartmentalized signalling: controlling cell proliferation and differentiation.
• Paul P.M. Schnetkamp, Ph.D. Structure-function studies of membrane proteins involved in cellular calcium and cGMP homeostasis (e.g. Na-Ca exchange and guanylyl cyclase).
• Yan Shi, M.D., Ph.D. Endogenous and microbial adjuvants, their receptors, in antigen presenting cell activation, natural antibodies and nucleic acid in immune regulation.
• Michael P. Walsh, Ph.D. Regulation of cellular functions by second messengers, with emphasis on protein phosphorylation and the control of smooth muscle contraction.
• Brent W. Winston, M.D. Study of the mechanisms of functional diversity of macrophages, encompasses examining macrophage activation, cell signalling and gene regulation.
• Dallan B. Young, Ph.D. Genetics and biochemistry of signal transduction in yeast and mammalian cells; emphasis on MAP kinase pathways; regulation of cell cycle, growth and differentiation.